Chloroquine as a prophylactic agent against COVID-19?
Identifieur interne : 001355 ( Main/Exploration ); précédent : 001354; suivant : 001356Chloroquine as a prophylactic agent against COVID-19?
Auteurs : Mathieu Gendrot [France] ; Emilie Javelle [France] ; Axelle Clerc [France] ; Hélène Savini [France] ; Bruno Pradines [France]Source :
- International journal of antimicrobial agents [ 1872-7913 ] ; 2020.
Descripteurs français
- KwdFr :
- Animaux (MeSH), Antipaludiques (usage thérapeutique), Antiviraux (usage thérapeutique), Association de médicaments (MeSH), Azithromycine (usage thérapeutique), Betacoronavirus (effets des médicaments et des substances chimiques), Cellules Vero (MeSH), Chloroquine (usage thérapeutique), Humains (MeSH), Hydroxychloroquine (usage thérapeutique), Infections à coronavirus (prévention et contrôle), Infections à coronavirus (traitement médicamenteux), Pandémies (prévention et contrôle), Pneumopathie virale (prévention et contrôle), Pneumopathie virale (traitement médicamenteux), Prophylaxie pré-exposition (méthodes).
- MESH :
- effets des médicaments et des substances chimiques : Betacoronavirus.
- méthodes : Prophylaxie pré-exposition.
- prévention et contrôle : Infections à coronavirus, Pandémies, Pneumopathie virale.
- traitement médicamenteux : Infections à coronavirus, Pneumopathie virale.
- usage thérapeutique : Antipaludiques, Antiviraux, Azithromycine, Chloroquine, Hydroxychloroquine.
- Animaux, Association de médicaments, Cellules Vero, Humains.
English descriptors
- KwdEn :
- Animals (MeSH), Antimalarials (therapeutic use), Antiviral Agents (therapeutic use), Azithromycin (therapeutic use), Betacoronavirus (drug effects), Chlorocebus aethiops (MeSH), Chloroquine (therapeutic use), Coronavirus Infections (drug therapy), Coronavirus Infections (prevention & control), Drug Therapy, Combination (MeSH), Humans (MeSH), Hydroxychloroquine (therapeutic use), Pandemics (prevention & control), Pneumonia, Viral (drug therapy), Pneumonia, Viral (prevention & control), Pre-Exposure Prophylaxis (methods), Vero Cells (MeSH).
- MESH :
- chemical , therapeutic use : Antimalarials, Antiviral Agents, Azithromycin, Chloroquine, Hydroxychloroquine.
- drug effects : Betacoronavirus.
- drug therapy : Coronavirus Infections, Pneumonia, Viral.
- methods : Pre-Exposure Prophylaxis.
- prevention & control : Coronavirus Infections, Pandemics, Pneumonia, Viral.
- Animals, Chlorocebus aethiops, Drug Therapy, Combination, Humans, Vero Cells.
DOI: 10.1016/j.ijantimicag.2020.105980
PubMed: 32294495
PubMed Central: PMC7152897
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Aix Marseille Univ, IRD, SSA, AP-HM, VITROME, Marseille, France; IHU Méditerranée Infection, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Unité Parasitologie et Entomologie, Département Microbiologie et Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, Marseille, France; Aix Marseille Univ, IRD, SSA, AP-HM, VITROME, Marseille, France; IHU Méditerranée Infection, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Javelle, Emilie" sort="Javelle, Emilie" uniqKey="Javelle E" first="Emilie" last="Javelle">Emilie Javelle</name><affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, SSA, AP-HM, VITROME, Marseille, France; IHU Méditerranée Infection, Marseille, France; Service des Maladies Infectieuses, Hôpital d'Instruction des Armées Laveran, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Aix Marseille Univ, IRD, SSA, AP-HM, VITROME, Marseille, France; IHU Méditerranée Infection, Marseille, France; Service des Maladies Infectieuses, Hôpital d'Instruction des Armées Laveran, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Clerc, Axelle" sort="Clerc, Axelle" uniqKey="Clerc A" first="Axelle" last="Clerc">Axelle Clerc</name><affiliation wicri:level="3"><nlm:affiliation>Service des Maladies Infectieuses, Hôpital d'Instruction des Armées Laveran, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service des Maladies Infectieuses, Hôpital d'Instruction des Armées Laveran, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Savini, Helene" sort="Savini, Helene" uniqKey="Savini H" first="Hélène" last="Savini">Hélène Savini</name><affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, SSA, AP-HM, VITROME, Marseille, France; Service des Maladies Infectieuses, Hôpital d'Instruction des Armées Laveran, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Aix Marseille Univ, IRD, SSA, AP-HM, VITROME, Marseille, France; Service des Maladies Infectieuses, Hôpital d'Instruction des Armées Laveran, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Pradines, Bruno" sort="Pradines, Bruno" uniqKey="Pradines B" first="Bruno" last="Pradines">Bruno Pradines</name><affiliation wicri:level="3"><nlm:affiliation>Unité Parasitologie et Entomologie, Département Microbiologie et Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, Marseille, France; Aix Marseille Univ, IRD, SSA, AP-HM, VITROME, Marseille, France; IHU Méditerranée Infection, Marseille, France; Centre National de Référence du Paludisme, Marseille, France. Electronic address: bruno.pradines@gmail.com.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Unité Parasitologie et Entomologie, Département Microbiologie et Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, Marseille, France; Aix Marseille Univ, IRD, SSA, AP-HM, VITROME, Marseille, France; IHU Méditerranée Infection, Marseille, France; Centre National de Référence du Paludisme, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author></analytic><series><title level="j">International journal of antimicrobial agents</title><idno type="eISSN">1872-7913</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals (MeSH)</term><term>Antimalarials (therapeutic use)</term><term>Antiviral Agents (therapeutic use)</term><term>Azithromycin (therapeutic use)</term><term>Betacoronavirus (drug effects)</term><term>Chlorocebus aethiops (MeSH)</term><term>Chloroquine (therapeutic use)</term><term>Coronavirus Infections (drug therapy)</term><term>Coronavirus Infections (prevention & control)</term><term>Drug Therapy, Combination (MeSH)</term><term>Humans (MeSH)</term><term>Hydroxychloroquine (therapeutic use)</term><term>Pandemics (prevention & control)</term><term>Pneumonia, Viral (drug therapy)</term><term>Pneumonia, Viral (prevention & control)</term><term>Pre-Exposure Prophylaxis (methods)</term><term>Vero Cells (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux (MeSH)</term><term>Antipaludiques (usage thérapeutique)</term><term>Antiviraux (usage thérapeutique)</term><term>Association de médicaments (MeSH)</term><term>Azithromycine (usage thérapeutique)</term><term>Betacoronavirus (effets des médicaments et des substances chimiques)</term><term>Cellules Vero (MeSH)</term><term>Chloroquine (usage thérapeutique)</term><term>Humains (MeSH)</term><term>Hydroxychloroquine (usage thérapeutique)</term><term>Infections à coronavirus (prévention et contrôle)</term><term>Infections à coronavirus (traitement médicamenteux)</term><term>Pandémies (prévention et contrôle)</term><term>Pneumopathie virale (prévention et contrôle)</term><term>Pneumopathie virale (traitement médicamenteux)</term><term>Prophylaxie pré-exposition (méthodes)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antimalarials</term><term>Antiviral Agents</term><term>Azithromycin</term><term>Chloroquine</term><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Pre-Exposure Prophylaxis</term></keywords><keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Prophylaxie pré-exposition</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Coronavirus Infections</term><term>Pandemics</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Infections à coronavirus</term><term>Pandémies</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antipaludiques</term><term>Antiviraux</term><term>Azithromycine</term><term>Chloroquine</term><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Chlorocebus aethiops</term><term>Drug Therapy, Combination</term><term>Humans</term><term>Vero Cells</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Association de médicaments</term><term>Cellules Vero</term><term>Humains</term></keywords></textClass></profileDesc></teiHeader></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32294495</PMID><DateCompleted><Year>2020</Year><Month>06</Month><Day>15</Day></DateCompleted><DateRevised><Year>2020</Year><Month>06</Month><Day>24</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1872-7913</ISSN><JournalIssue 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J. Antimicrob. Agents</ISOAbbreviation></Journal><ArticleTitle>Chloroquine as a prophylactic agent against COVID-19?</ArticleTitle><Pagination><MedlinePgn>105980</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0924-8579(20)30137-0</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ijantimicag.2020.105980</ELocationID><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gendrot</LastName><ForeName>Mathieu</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Unité Parasitologie et Entomologie, Département Microbiologie et Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, Marseille, France; Aix Marseille Univ, IRD, SSA, AP-HM, VITROME, Marseille, France; IHU Méditerranée Infection, Marseille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Javelle</LastName><ForeName>Emilie</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, SSA, AP-HM, VITROME, Marseille, France; IHU Méditerranée Infection, Marseille, France; Service des Maladies Infectieuses, Hôpital d'Instruction des Armées Laveran, Marseille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Clerc</LastName><ForeName>Axelle</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Service des Maladies Infectieuses, Hôpital d'Instruction des Armées Laveran, Marseille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Savini</LastName><ForeName>Hélène</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, SSA, AP-HM, VITROME, Marseille, France; Service des Maladies Infectieuses, Hôpital d'Instruction des Armées Laveran, Marseille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pradines</LastName><ForeName>Bruno</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Unité Parasitologie et Entomologie, Département Microbiologie et Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, Marseille, France; Aix Marseille Univ, IRD, SSA, AP-HM, VITROME, Marseille, France; IHU Méditerranée Infection, Marseille, France; Centre National de Référence du Paludisme, Marseille, France. 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